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    Clinical Study Shows That Natural Acne Treatment As Good As Leading Prescription Drug

  • Summary

    Clinical evidence of the effectiveness of Bioskinforte, a natural acne treatment balm meant for both spot treatments and overall application on face or back, is available. The product includes five natural anti-acne powerhouses and most noticeably Helix aspersa snail secretions that contain: a) “glycans” or sugar (complex carbohydrate) molecules that replenish hyaluronic acid, the moisturizer magnet of the skin, b) powerful antioxidant enzymes, and c) soluble proteins and copper peptides with properties that regenerate the cells and tissues lining the walls of the sebum ducts which suffer several types of injurious attacks that cause acne inflammation.

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    Dermatologists know that the mere presence of P. acnes does not cause acne.  Even the uncontrolled multiplication of P. acnes bacteria is not the sole contributing factor to the development of acne.  Bacteria only begin aggravating acne inflammation when they multiply uncontrolled and produce chemical wastes that corrode and injure the cells lining the walls of the sebum ducts. This happens when pores get clogged, as such bacteria multiplies only in an environment free of oxygen.

    Victoria O’Driscoll, dermatologist in R&D at Andes Natural, unveils a few truths about acne in general and the Bioskinforte acne treatment balm:

    “Linoleic deficiency in the sebaceous glands leads to the production of a type of sebum that is not as liquid as it needs to be to outflow swiftly out to the surface of the skin. Instead it is hardened and it punctures or cuts and injures the cells lining the walls of the sebum ducts as if the sebum had become nails or razor blades”. She says: “it is the early signals of a depletion of linoleic fatty acids and the injurious attacks to the cells in the sebum ducts by hardened sebum what causes the inflammatory reaction that characterizes acne and may lead to demeaning acne scars”.

    One can imagine what ensues when a splinter, or a rose thorn, perhaps a cactus prickle, injures living cells or when the quill of a porcupine injures a finger.  All the symptoms of inflammation emerge: swelling, heat, pain, redness, and a certain degree of impairment in normal functioning.  Inflammation produces volumes of free radicals, which also damage the cells and furthers  inflammation.  The cells often respond to puncturing or severing injuries and free radical attacks by thickening the matrix around them or increased cellular layering.

    When those cells die periodically and are sloughed off, they mix with hardened sebum creating a sticky paste that clogs the pores. Inside clogged pores bacteria start reproducing and the waste chemicals of their metabolism corrode and thus also injure the cells in the hair follicles, which again furthers the never-ending cycle of inflammation.

    Victoria adds: “acne is more likely during puberty, times of stress and fluctuating hormones (especially in premenstrual and pre-menopausal women) because then the adrenal glands trigger the production of too much sebum and depletion of linoleic acid ensues. But also certain prescription drugs, and comedogenic airborne or materials applied to the skin surface can clog the pores”.

    Acne-prone skin should be treated differently than skin with other issues (dryness, aging, etc.). Recognizing a need for a multi-prong approach to treating acne, Biocutis created a gentle healing balm, a light cream-gel that is incredibly moisturizing and allows for application of foundation with no concern.

    Knowing what causes acne inflammation has shed light on five key areas that contribute to acne and need to be addressed.  The five are: injuries to the cells lining the walls of the sebum ducts, increased oil production, a proliferation of the normal bacteria that live on skin and inside the sebum ducts, hardening of the sebum because of depletion of linoleic acid in the sebaceous glands, and an immoderate inflammatory response.

    Thus, the prevention and healing balm is formulated to provide five crucial anti-blemish benefits: healing of damaged cells and tissues, oil-reducing to prevent future breakouts, antibacterial action, liquefying of sebum and dissolution of the sticky paste that clogs pores, and anti-irritant to calm inflamed skin.

    With clinical evidence of the effectiveness of Bioskinforte for acne treatment from a double blind study with 96 adults and teens affected by acne, Andes Natural is re-launching Bioskinforte balm, a highly effective yet gentle approach for treating acne right at home.  In the 12 week acne reduction study linked above, Bioskinforte was used by half of the group and was shown to treat blemishes with results as good as a leading topical acne prescription drug used as control by the other half of the volunteers; and without any side effects.

    Since acne can really have a negative impact on someone’s self-esteem, and prescriptions may have undesired side effects, to be able to make such a strong clinical claim regarding the results that Bioskinforte delivers is very exciting.  Anyone suffering from blemishes now has the opportunity to clear acne with natural actives that have shown no side effects but results on par with what one could achieve with a prescription topical drug or in a dermatologist’s office.

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    “Inflammation starts way before acne lesions show up on the skin surface. Acne inflammation is triggered by signals from the immune cells residing among skin tissues of a deficiency of essential fatty acids (linoleic) in the sebum glands because of a dilution effect of high sebum production”. Inflammatory Events Are Involved in Acne Lesion Initiation – Journal of Investigative Dermatology (2003) 121, 20–27. Anthony HT Jeremy, Diana B Holland, Susan G Roberts, Kathryn F Thomson and William J Cunliffe. Department of Dermatology, University of Leeds, and Leeds General Infirmary, Leeds, UK.
    - Mariel Claude Niel, Dermatologist
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    Victoria O Driscoll



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